Ukunakekelwa kwesikhumba kulandela izizathu ezimbili eziyinhloko: okusheshayo anti-ukuguga kanye nokuvuselelwa kwesikhumba okuzinzile.
Abantu abaningi baqala ukujula kwezinyawo ze-crow kanye nokugoba kwe-nasolabial ngenxa yokubukeka kobuso okuvamile, futhi balindele ukuqina kwesikhumba okubonakalayo kanye nokushelela kwemibimbi ngemva kokusetshenziswa kwesikhumba. Okwamanje, isikhumba siphathwa ngendlela engangenisi kakhulu. yezimonyo Izinqubo ezifana ne-microneedling kanye nokwelashwa nge-laser zivame ukuba bomvu, ukoma okuqinile kanye nezithiyo zesikhumba ezithintekile. Kulesi simo, isikhumba sidinga ukululama kancane kancane, okuqhubekayo ukuze sibuyisele isimo saso esinempilo nesizinzile kunokuguqulwa ngokushesha.
Izithako ezimbili zezitshalo ezinamandla zihlangabezana kahle nalezi zidingo ezahlukene. I-Spilanthol inikeza imiphumela yokulwa nemibimbi kanye nokuqina ngokushesha, kuyilapho i-TECA Centella Triterpenes ejwayelekile igxile ekuthobeni nasekulungiseni isikhumba ngemuva kwenqubo. Kulolu cwaningo, senza izivivinyo zabantu zemitholampilo ukuqinisekisa ukusebenza kwangempela kwalezi zithako zombili ngedatha eqinile yobufakazi.
Ingxenye 01 Ukuvimbela Ukuguga Okusheshayo: I-Spilanthol Isebenza Ngokushesha Kangakanani?
Izinyawo ze-Crow, ukugoba kwe-nasolabial kanye nemigqa ye-glabellar, imibimbi yobuso eyinkinga kakhulu kwabesifazane abaningi, ikakhulukazi imibimbi enamandla ebangelwa ukunyakaza kobuso okuphindaphindiwe. Lezi yizinkinga eziphezulu zobuhle abasebenzisi abalindele ukuthi zithuthuke ngokushesha.
Kuthathwe ku-tropical I-Acmella oleracea, i-spilanthol isebenza njengesitshalo semvelo esinamandla kakhulu sokulwa nokuguga. Idume ngendlela yayo eyingqayizivele yokuqinisa, isibe yisithako esiyinhloko sokwakheka okusheshayo kokulwa nemibimbi.
Ngokungafani nemithi evamile yokuthambisa ukuguga, i-spilanthol inezindlela ezimbili zokunciphisa imibimbi nokuqinisa isikhumba. Ivimbela kancane ukudluliselwa kwemizwa yemizwa yobuso, iphumuza imisipha yobuso ecindezeleke kakhulu futhi ivimbele ukujula kwemibimbi okubangelwa ukubonakaliswa. Ngaphezu kwalokho, ivuselela umsebenzi we-dermal fibroblast, iqinisa isakhiwo se-collagen fiber, iqinise isikhumba esigobile futhi ithuthukise ukuthungwa okuqinile.
Ingaletha imiphumela ebonakalayo ngokushesha kangakanani? Ingabe iqala ukusebenza ngemizuzu engama-20 noma ngaphezulu? Ukuhlolwa kwezokwelapha kwabantu okulawulwayo kunikeza izimpendulo ezinembile.
I-Clinical Trial Protocol
Kwenziwa isivivinyo esizilawulayo sobuso obuhlukene. Uhlangothi lwesobunxele lwe ubuso kwelashwe nge-essence equkethe i-spilanthol engu-0.026%, kanti uhlangothi lwesokudla lwelashwe nge-spilanthol ephezulu engu-0.05%. Ukushintsha kokwakheka kwesikhumba kwezinyawo ze-crow kanye nokugoba kwe-nasolabial kwalinganiswa ngokunembile ngezinhlelo zochwepheshe ze-3D skin imaging ngezikhathi ezine: isisekelo, imizuzu engama-20, imizuzu engama-40 kanye namahora ama-2 ngemuva kokufakwa.
Okutholakele Okubalulekile Komtholampilo
1. Izinyawo ZikaCrow: Ukuthuthuka Okuphezulu Kubonwa Emahoreni Ama-2
I-Spilanthol ihlasela ngokushesha imibimbi ye-periocular ngempumelelo encike ekugxilweni. Iqembu elinokugxila okuphezulu okungu-0.05% lithole ukuthuthuka okukhulu emahoreni ama-2 ngemuva kokusetshenziswa:
▪️ Ukunciphisa ivolumu yokushwabana: 12.68%
▪️ Ukunciphisa indawo yokushwabana: 14.33%
Kungakapheli amahora amabili nje, kokubili ukujula kanye nokumbozwa kwemigqa emincane ye-periocular kwancipha ngokusobala.
2. Ukugoba Kwesikhumba: Ukuqinisa Isikhumba Nokuthuthukiswa Kokugoba
Kuphinde kwabonakala ukuthuthuka okuphawulekayo emafolweni e-nasolabial, indawo yobuso evame ukuguga kakhulu, eqenjini le-spilanthol elingu-0.05% ngemva kwamahora ama-2:
▪️ Ukunciphisa ivolumu yokushwabana: 10.70%
▪️ Ukunciphisa indawo yokushwabana: 10.52%
Ukulungiswa okuvumelanisiwe kwemibimbi ye-periocular kanye ne-mid-face kuqinisekisa ukuthi i-spilanthol iyindlela esezingeni eliphezulu yokulungisa imibimbi eqondile kanye nokuqinisa isikhumba ngokushesha.
3. Ukuthuthukiswa Okubonakalayo Kokubona Kungakapheli Imizuzu Engama-20
Ngaphezu kwedatha yezinsimbi, izithombe ezitholakala endaweni eyodwa ziqinisekisa izinguquko zesikhumba ezinembile. Imizuzu engamashumi amabili ngemva kokusetshenziswa kwe-spilanthol, imigqa emincane ye-periocular engaphezulu iyashelela, ukuthungwa kwesikhumba kuba ngcono futhi kube buthakathaka, kanti isikhumba esigobile sibonisa ukuqina okubonakalayo.
IsifinyezoI-Spilanthol inikeza imiphumela yokuqala yokulwa nemibimbi ngemizuzu engama-20 futhi ifinyelela ukusebenza kahle kakhulu emahoreni ama-2, ifiphaza ngempumelelo imigqa yokubonakaliswa kanye nemigqa emincane engaphezulu ukuze isikhumba siqine ngokushesha, sibonakale.
Izicelo Zomkhiqizo Ezisunguliwe ze-TECA Centella Triterpenes
1. I-Centellian24 (i-Dongkook Pharmaceutical, eNingizimu Korea)
Njengophawu lokulinganisa lohlelo lokusebenza lwe-TECA, i-Centellian24 isebenzisa amashumi eminyaka obuchwepheshe be-TECA centella triterpene obunelungelo lobunikazi obuthuthukiswe yi-Dongkook Pharmaceutical. Ifomula yayo eyinhloko isuselwa ku-Madecassol, isithako sokulungisa sezokwelapha esivamile esinokuphepha nokusebenza kahle kokulungisa okuqinisekisiwe ngokwezokwelapha.
Imikhiqizo ethengiswa kakhulu okubalwa kuyo i-Madeca Repair Cream, i-Anti-Aging Time Cream kanye ne-PDRN Active Essence isebenzisa ama-TECA complexes ajwayelekile anezinga eliphezulu lokugxila elinezilinganiso ezilungiselelwe ze-centella actives ezintathu eziyinhloko. Le mikhiqizo igxile ekubuyiselweni kwezivimbelo ngemuva kwenqubo, ukuqeda ukubomvu kanye nokuqina kwesikhumba okubucayi, okuqashelwa kabanzi njengokunakekelwa kwesikhumba okubalulekile ngemuva kokwelashwa emitholampilo yobuhle yaseKorea kanye nokusatshalaliswa emhlabeni jikelele. Ubuchwepheshe obuthuthukisiwe be-Active-TECA buhlanganisa izinzuzo zokulungisa kanye nokulwa nokuguga ukuze kuncishiswe ukugoba kanye nokufiphala kwesikhumba esonakele.
2. Isikhumba1004 eMadagascar
Igxile ezithakweni zezitshalo zaseMadagascar ezimsulwa, i-Centella TECA Repair Cream yalo mkhiqizo yakhiwe ngobuchwepheshe be-TECA obuthuthukisiwe obuyi-50X obuphinda ngokunembile izingxenye ezintathu eziyinhloko ze-triterpene. Iqukethe ifomula encane, engenakho ukucasuka, inikeza ukunciphisa ukubomvu kwansuku zonke, ukuqinisa izithiyo kanye nokukhululeka kokuzwela, efanelekile ukuzinza njalo kanye nokululama okuncane ngemva kwenqubo. Ingumkhiqizo wokulungisa wezokwelapha odumile emhlabeni jikelele futhi ongabizi kakhulu.
3. Ulayini Wokuphola Nokulungisa we-CeraVe Centella (eFrance)
Umkhiqizo ohamba phambili emhlabeni wonke wokunakekelwa kwezithiyo, uchungechunge lwe-Centella lwe-CeraVe lusebenzisa indlela ejwayelekile ye-Centella triterpene ehambisana nezimiso zobuchwepheshe ze-TECA. Igcina i-asiaticoside emsulwa, i-asiatic acid kanye ne-madecassic acid ngaphandle kokungcola okungalungile noma i-fusel alcohol. Lo mugqa unikeza ukukhululeka okuthambile kokubomvu kanye nokuvuselelwa kwezithiyo, okulungele ukuthobisa isikhumba esibucayi kanye nokulungiswa okuyisisekelo kwenqubo yokwelapha ngemuva kokugcoba. Ngokwakheka okulula, ungomunye wemikhiqizo esekwe ku-TECA eyaziwa kakhulu. ukunakekelwa kwesikhumba imigqa.
4. I-Keyinme Centella Repair Series (China)
Njengomkhiqizo ohamba phambili wasekhaya wokunakekelwa kwesikhumba ngemuva kwenqubo, i-Keyinme isebenzisa i-centella triterpenes ehlanganisiwe ehlanzekile kakhulu ehambisana ne-TECA repair logic ejwayelekile. Njengoba idlula umphumela owodwa wokuthambisa we-centella extracts evamile, igxile ekulweni nokuvuvukala, ekunciphiseni ububomvu, ekulungiseni i-keratin kanye nasekuqiniseni isikhumba isikhathi eside. Ukusetshenziswa okuqhubekayo ngemuva kwe-microneedling kanye nokwelashwa nge-laser kunciphisa ngokushesha ububomvu obuvuthayo futhi kusheshise ukuphulukiswa kwezithiyo.
5. I-SkinCeuticals Soothing Repair Serum (Ifomula Ye-Centella Elungiselelwe)
Isebenza ngobuchwepheshe be-centella triterpene obuhlanganisiwe, le fomula ithuthukisa ukusebenza kokulungisa okuhambisanayo kwemisebenzi emithathu eyinhloko. Yakhelwe isikhumba esizwela kakhulu futhi esithinteke ngemva kwenqubo, ifinyelela ukuthobisa okusheshayo okulwa nokuvuvukala, ukuvuselelwa okujulile kwezivimbelo kanye nokuzinza kwesikhumba isikhathi eside. Ngomsebenzi ophezulu we-bioactive kanye nokuvuleka, inakekela ukunakekelwa kwesikhumba okuthambile kwe-post-process.
Ingxenye 02 Ukuvuselelwa Kwezithiyo Zesikhathi Eside nge-TECA Centella Triterpenes
I-Cosmetic izinqubo ezifana ne-microneedling kanye nokwelashwa nge-laser kuphazamisa okwesikhashana i-stratum corneum futhi kuphazamisa ukusebenza kwesithiyo sesikhumba, okuholela ekubeni bomvu obuqhubekayo, ukushisa okushisayo, ukuqina okomile kanye nokuzwela ngokweqile. Kulesi sigaba sokululama, isikhumba sibeka phambili ukududuza, ukukhulula ububomvu kanye nokubuyiselwa kwesithiyo kunokwelashwa kokulwa nokuguga noma ukukhanyisa.
Izithako ze-centella ezivamile zinikeza imiphumela elinganiselwe yokuthoba enobukhulu obulodwa. Ngokuphambene nalokho, i-TECA Centella Triterpene Complex ejwayelekile iyindlela yokulungisa ethuthukisiwe equkethe izingxenye ezintathu eziyinhloko ezisebenzayo: i-asiaticoside, i-asiatic acid kanye ne-madecassic acid. Isebenza ngezindlela eziningi ukuze kuncishiswe ukuvuvukala, kulungiswe izithiyo zesikhumba futhi kuzinziswe isikhumba esisengozini ngemuva kwenqubo.
Ukwelashwa nge-microneedling kanye ne-laser kuphazamisa okwesikhashana ungqimba lokuvikela lwesikhumba, kunciphisa ukuzivikela kwe-epidermal futhi ngokushesha kusunduze isikhumba sibe sesimweni sokuzwela ngokweqile. Izimpawu ezivamile zifaka phakathi ukubomvu okukhulu, ukusha kwendawo, ukungakhululeki okuhlabayo, ukuqina okomile okuqhubekayo kanye nokugcinwa kwamanzi okuphazamisekile. Isikhumba sisabela kakhulu ekushintsheni kwezinga lokushisa kanye nezinto zokunakekelwa kwesikhumba zangaphandle, sithambekele ekubeni nokubomvu nokucasuka okuphindaphindiwe.
Iphutha elivamile lokunakekelwa kwesikhumba ngesikhathi sokululama ukuqhubeka nemikhuba eqinile yokulwa nokuguga, ukukhanyisa kanye nokukhipha amabala, okucindezela isikhumba esonakele futhi kulibazise ukuvuselelwa kwezithiyo.
Izithako ezijwayelekile ze-centella ziqukethe kuphela izingxenye ezisebenzayo eyodwa, zinciphisa ukoma okuphezulu kanye nokubomvu ngemiphumela yokulungisa ebuthakathaka, engapheli. Njengenhlanganisela ekhethekile yokulungisa okuhlanzekile okuphezulu kwesikhumba esizwela ngemuva kwenqubo, i-TECA ilinganisa ngokunembile ama-triterpenes amathathu ayisisekelo ngezindlela ezihambisanayo: i-asiaticoside inikeza ukuthambisa okunamandla okulwa nokuvuvukala ukuze kuqedwe ukusha, ukubomvu kanye nokuhlaba ngemva kokwelashwa; i-asiatic acid ilungisa izithiyo ezonakele futhi ikhuthaza ukuvuselelwa kwe-keratinocyte; i-madecassic acid igcina ukuthambisa isikhathi eside, inciphisa izimpendulo zokucindezeleka kwesikhumba futhi ivimbele ukuzwela okuphindaphindiwe kanye nokubomvu.
Ingabe ukusebenza kahle kokulungisa kwe-TECA kuqiniswe noma kumane kuyi-hype yokukhushulwa? Senze isivivinyo esilawulwayo sokuhlukanisa ubuso esihlala isikhathi eside sezinsuku ezingu-14 sigxile ezinqubweni ezimbili zobuhle ezivamile: i-microneedling kanye nokwelashwa nge-laser.
I-Clinical Trial Protocol
Kwenziwa ucwaningo olulawulwa ubuso obuhlukene. Uhlangothi olulodwa lobuso lwasetshenziswa ngokhilimu ofakwe i-TECA, kanti uhlangothi oluphambene lusebenzise ukhilimu we-placebo ongasebenzi ongenalutho. Izimo zesikhumba zaqashwa ngemizuzu engama-30, izinsuku ezi-3 kanye nezinsuku eziyi-14 ngemuva kokusetshenziswa. Ukusebenza kahle kokulungisa kwahlolwa ngokuphelele ngokulahlekelwa amanzi nge-transepidermal (TEWL), indawo ebomvu, i-erythema index (EI) kanye nokuhlaziywa kwesithombe sesikhumba se-VISIA.
Okutholakele Okubalulekile Komtholampilo
1. Ukulungiswa Ngemva Kokukhuliswa Kwengane: Ukuqinisa Izithiyo Nokunciphisa Ukubomvu Okusheshayo
Ngemva kwezinsuku ezingu-14 zokusetshenziswa okuqhubekayo, uhlangothi oluphathwe yi-TECA lubonise ukuthuthuka okuphezulu kakhulu uma kuqhathaniswa neqembu lokulawula:
▪️ Ukuncipha kwe-TEWL: 29.47% (ukugcinwa kwamanzi esikhumbeni kuthuthukiswe kakhulu)
▪️ Ukunciphisa indawo ebomvu ebusweni: 27.35%
Ukuhlolwa kwe-VISIA kuqinisekisile ukufiphala okuqhubekayo kwezilonda ze-erythema, ukululama kancane kancane kwezithiyo kanye nokuzinza kwesikhumba okuqhubekayo ngokuhamba kwesikhathi.
2. Ukulungiswa Ngemva Kwe-Laser: Ukududuza Okusheshayo Kwemizuzu Engama-30 Nokuvuselelwa Okugcwele Kwezinsuku Eziyi-14
Isikhumba esiphathwe nge-laser sihlushwa ukusha okukhulu kanye nokubomvu. I-TECA ibonisa izinzuzo ezimbili zokuthobisa okusheshayo kanye nokuvuselelwa kwesikhathi eside, idlula iqembu lokulawula kulo lonke umjikelezo wokubuka. Imininingwane eyinhloko ngemuva kwezinsuku ezingu-14 zokwelashwa yilena elandelayo:
▪️ Ukuthuthukiswa kwezithiyo zesikhumba sekukonke: 23.19%
▪️ Ukuthuthukiswa kwenkomba ye-erythema: 18.42%
▪️ Ukuthuthukiswa kwendawo ebomvu ebusweni: 37.92%
I-TECA iqeda ngokushesha ukubomvu okushisayo zingakapheli imizuzu engama-30, izinzise izimo zesikhumba zingakapheli izinsuku ezi-3, futhi ivuselela ngokuphelele izithiyo ezithintekile ezinsukwini eziyi-14, okwenza kube lula ukubuyiselwa kancane kancane kwe-physiology yesikhumba esinempilo yesikhumba esisengozini ngemuva kwenqubo.
Amacala Okusetshenziswa Komkhiqizo we-Spilanthol
1. I-Biotulin Anti-Wrinkle Serum (e-UK)
I-Biotulin iyi-serum yokulwa nokuguga esekwe ku-spilanthol ethengiswa kakhulu emhlabeni futhi iyintandokazi phakathi kosaziwayo baseYurophu nabaseMelika. Ifaka ukushelela imibimbi okusheshayo kwehora eli-1 futhi imelela ukusetshenziswa kwezimboni okunegunya kakhulu kwe-spilanthol. Yenziwe ngobumsulwa obuphezulu I-Acmella oleracea I-extract, ikhipha i-spilanthol enamandla ukuze ikhulule kancane imisipha eveza ubuso kanye nezinyawo ze-crow ezibushelelezi ngokushesha, imigqa ye-glabellar kanye nemibimbi eguquguqukayo ye-perioral, ifinyelele ukuqina kwesikhumba okusheshayo okungahlaseli kanye nokunciphisa imibimbi.
2. I-DMS Dermatologic Micro-Liposome Anti-Aging Firming Serum (eJalimane)
Umkhiqizo ochwepheshe omnene wokulwa nokuguga onefomula ehlanzekile, engenaphunga futhi engacasuli. Igxile ku-spilanthol ekwazi ukungena kalula futhi ihlanganiswe nezinhlelo zokuthambisa i-amino acid, ilinganisela ukushelela kwemibimbi okusheshayo kanye nokulungisa isikhumba okuthambile. Ihlose imigqa engacacile kanye nemibimbi engaphezulu ebangelwa ukubukeka kobuso okuphindaphindiwe, ikhulula ukucindezeleka kwemisipha futhi icwenge isikhumba esiqinile, esigobile, esifanele ukunakekelwa kwansuku zonke kokulwa nokuguga kwesikhumba esizwelayo nesibuthakathaka.
3. I-Proya Chrono Oil Enomsoco Enondla Ubuso
Lo mkhiqizo usebenzisa uhlelo olunemiphumela emibili oluhlanganisa i-spilanthol ne-ascorbic acid derivatives ukuze kufezwe ukushelela kwemibimbi okusheshayo kanye nokuvikelwa kwe-antioxidant yesikhathi eside. Ngokuphumuza imisipha yobuso, i-spilanthol iqeda imibimbi yesikhashana eguquguqukayo ebangelwa ukuhlala ubuthongo kuze kube sebusuku kanye nokubonakaliswa kobuso okuvamile futhi inciphise ukuvuvuka nokuwa kobuso. Isisekelo samafutha ezitshalo avutshiwe siqinisekisa ukungena okuphezulu kanye nokuthungwa okungeyona i-comedogenic, okulungele ukunakekelwa kwasekuqaleni kokulwa nokuguga kanye nokuqina okuphuthumayo ngaphambi kokwenza izimonyo.
4. Isicelo se-Azelis Standardized Spilanthol Raw Material
Umhlinzeki wezithako ohamba phambili emhlabeni wonke i-Azelis wethula i-Gatuline® Expression AF, iMadagascar ejwayelekile I-Acmella oleracea Ikhishwa nge-spilanthol egxilile kakhulu. Iqinisekiswe ngokuhlolwa okubanzi kwe-in-vitro kanye nokuhlolwa kwabantu, ivimba ngempumelelo ukufinyela kwemisipha futhi ithuntubeze imibimbi enamandla. Lesi sithako sisetshenziswe kabanzi kuma-serum okuqinisa, okhilimu bokulwa nemibimbi kanye nokhilimu wamehlo ngamakhulu emikhiqizo yokunakekelwa kwesikhumba emhlabeni jikelele.
I-Leecosmetic: Ukusebenzisa izinto ezingavuthiwe ezivela ezinkampanini ezidumile emhlabeni jikelele
I-Leecosmetic a umkhiqizi wezimonyo ohamba phambili. Ihlinzeka ngemikhiqizo yezimonyo yekhwalithi ephezulu ngamanani ancintisana kakhulu kanye nenani eliphansi le-oda elincane.
Sinikeza uhla lwezinsizakalo, njenge ukukhiqizwa kwezimonyo ngelebula yangasese, Ukukhiqizwa kwe-OEM/ODM, futhi unikeze isisombululo esiphelele sokuhlinzeka ngomkhiqizo wemikhiqizo yezimonyo ezincane neziphakathi nendawo.
Njengomkhiqizi wezimonyo welebula yangasese okhula ngokushesha, i-Leecosmetic ibilokhu isebenzisa izinto ezingavuthiwe ezivela ezinkampanini ezidumile emhlabeni wonke ngendlela ephephile nephumelelayo.
Xhumana: https://leecosmetic.com/contactus/
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- Azelis. (2022). Idokhumenti Yobuchwepheshe ye-Gatuline® Expression AF: Ucwaningo Lwezokwelapha Lwabantu ku-Spilanthol Lokunciphisa Umbimbi OguquguqukayoIzithako ezisebenzayo ze-Azelis Iphepha Elimhlophe.
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- Iqembu Locwaningo Lwe-Biotulin. (2020). Ukuhlolwa kwe-In-Vivo kwe-Acmella oleracea Extract equkethe i-Spilanthol ukuze kuphumule ngokushesha imigqa yokubonakaliswa kobusoIzimonyo, 7(3), 64.
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